Simplistic title. But in more detail, how do human bodies regulate around the same temperature without calibration, reference points, etc? I know the hypothalamus controls processes to raise and lower temperature, but what mechanism is a reference for the set point? And does the body have a way to calibrate that set point? Does your brain have a tiny ice bath and boiling pot for reference? From the day I was born, I’ve never had a NIST certified calibration on my hypothalamus and yet my body still averages 98.6 somehow. Of course, body temp varies with a number of factors, but it always works its way back to the set point. Whence comes the set point? #science source