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University of Waterloo researchers have successfully…

University of Waterloo researchers have successfully engineered soil bacteria to "eat" cancer tumors from the inside out. The bacteria target the oxygen-starved core of tumors, leaving healthy, oxygen-rich tissue completely untouched

This breakthrough uses *Clostridium sporogenes*, a bacterium that naturally thrives only in zero-oxygen environments—exactly like the center of a solid tumor.

The researchers added a "genetic circuit" (using DNA like wires) that acts as a safety switch. It only turns on the bacteria's survival and cancer-fighting traits once they've reached a high enough population inside the tumor. This prevents the bacteria from growing in oxygen-rich areas like the bloodstream, making it a highly targeted "guided missile" for cancer.
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