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Repeat COVID-19 vaccinations elicit antibodies that neutralize variants, other viruses. Unlike immunity to influenza, prior immunity to SARS-CoV-2 doesn’t inhibit later vaccine responses. Rather, it promotes development of antibodies against variants and even some distantly related coronaviruses.
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Repeat COVID-19 vaccinations elicit antibodies that neutralize variants, other viruses | Washington University School of Medicine in St. Louis

Response to updated vaccine is shaped by earlier vaccines yet generates broadly neutralizing antibodies

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