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ELI5: Need help understanding chromosome fusion and it’s significance

I need help understanding:
- what exactly does a chromosome do? (Besides carry dna) and why does it matter when there is a fusion?
- what specifically happened when the fusion happened? What did it do? What were the effects?
- what is the significance? Why is this a big deal?

Sorry if this sounds dumb, biology has always been confusing for me to understand. As a side hobby I’ve been studying about evolution and anthropology and stuff. I was reading about how humans chromosome count went to 48 to 46 and it’s this big thing in science but I’m struggling to understand what exactly it means. Thank you




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