It's a disaster thriller movie set on a train. It's a story of the train passengers that got exposed to a deadly disease by an infected passenger. When the government knew about it, everyone on board was quarantined and it was also rerouted to pass the unsafe Cassandra Crossing bridge. As the passengers learned the truth, they struggled to save themselves. Some tried to stop the train before it reached the bridge but many died when part of the train got over the collapsing bridge.